Neuroimaging Data
Processed measures from brain magnetic resonance imaging (MRI) exist for some participants in the Adult Changes in Thought (ACT) Study. These measures, provided by the ACT Neuroimaging Core, come from a mix of clinical MRI scans that were abstracted from medical records of consenting ACT participants and research MRI scans that were conducted among select samples of participants.
Study Forms
Not applicable. Because these data elements are derived directly from neuroimaging scans and radiologists’ interpretation, no forms are used to collect these data from participants.
Key Publications
The following publications provide additional detail on the neuroimaging data elements. These may be helpful supporting citations when publishing analyses using these data.
Groot C, Grothe MJ, Mukherjee S, Jelistratova I, Jansen I, van Loenhoud AC, Risacher SL, Saykin AJ, Mac Donald CL, Mez J, Trittschuh EH, Gryglewski G, Lanzenberger R, Pijnenburg YAL, Barkhof F, Scheltens P, van der Flier WM, Crane PK, Ossenkoppele R. (2021). Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer's disease subgroups. Neuroimage Clinical, 30, 102660. doi.org/10.1016/j.nicl.2021.102660.
Data Dictionary
A data dictionary is available to provide additional information about ACT data variables.